Case vignette: A 24yo M with no past medical history presents with a "boil" on his lower back that he noticed a couple days ago. The boil has been slowly increasing in size and becoming more tender. He denies fever, chills, nausea, vomiting, or history of previous abscesses. On exam there is a 3cm cutaneous abscess with confirmed fluid pocket on ultrasound, and there is minimal surrounding erythema or induration. You decide to incise and drain (I&D) the abscess, including probing to break up loculations and manual decompression, but you are not sure whether you need to irrigate the cavity.
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The Toxic Shelf: Mad Honey Poisoning
Illustrative Case: a 48-year-old man with chief complaint of dizziness. Additional complaints include perioral paresthesias, nausea, vomiting, generalized fatigue, and a possible syncopal episode. He seems confused and cannot add much history, but his family states that he may have ingested something he purchased from the internet.
Initial vitals include HR 33, BP 80/65, Oxygen saturation 98% on RA, temperature 36.7.
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PharmD Pearls: PPI in GI Bleeds - What's Your Route?
Clinical Conundrum: Is there an efficacy difference between IV or PO PPI in managing GI bleeds? Can you use PO or only IV?
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