EM Perles: For your ED pharmacology pearls

Clinical Conundrum-Patient case and labs come back post-intubation using succinylcholine and Oops the potassium is high? When does the increase in serum potassium occur (onset) and how long (duration) does it last after giving a single dose of succinylcholine for intubation? Does having renal failure in a patient change the onset and duration?

EM Perles: For your ED pharmacology pearls

Clinical Conundrum:

• How do you transition a patient from a nitroglycerin infusion to an alternative route of administration when there are no critical care beds?

EM Perles: For your ED pharmacology pearls

Clinical Conundrum:

• Do direct oral anticoagulants (DOACs) require overlapping or “bridging” with low molecular weight heparin (example: enoxaparin) or unfractionated heparin upon initiation of therapy?